Participants completed two sessions: a screening session and an imaging session. Screening sessions were held at a private research lab, where participants completed a series of self-report questionnaires (listed above) and the Pocket Smell Test (to assess for normal sense of smell; Sensonics, Inc.). Participants were scheduled for imaging if they met inclusion criteria (average of 32 days between screening session and scan day). They were asked to refrain from alcohol consumption for 3 days prior to the study. On the imaging day, participants reported to the Indiana University Clinical Research Center between 8 and 10 a.m. and were provided with a light, standardized breakfast. Vitals were checked, and repeat drug and pregnancy urine screens were conducted. Participants were then escorted to the imaging suite, where they rated current alcohol craving by responding to a subset of items on the Alcohol Craving Questionnaire (ACQ; Singleton et al., 2000) and current mood using the Affect Grid (Russell et al., 1989). As a comparison, subjects were also asked to rate their craving for grape juice (used as an appetitive control; AppCo) by responding to the same ACQ items (but rephrased for grape juice).
