sensitivity is an inherited trait. In view of this, our findings are consistent with the hypothesis that the risk of alcohol dependence associated with the A allele at SNP4, the G allele at SNP5, and the C allele at SNP6 in 2 population studies (Covault et al., 2004; Lappalainen et al., 2005) may, in part, be mediated by the decreased subjective responses to alcohol in individuals homozygous for these alleles.
