tonic-clonic seizures. Findings included volume loss and atrophy in both cerebrum and cerebellum, associated with increased ventricular volume and thinning of the corpus cal-losum. The greatest volume loss was seen in the parietal lobes. Multiple foci of increased signal intensity throughout white matter of the periventricular, deep, and subcortical areas were present, much more than would be expected for an individual of his age.