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Chunk #35 — DISCUSSION

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Prevention of Early Substance Use Mediates, and Variation at SLC6A4 Moderates, SAAF Intervention Effects on OXTR Methylation.
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methylation to see if they may be useful as rapid indicators of program success. To the extent that other biomarkers of resilience can be identified, it will also be useful to investigate the role of SAAF in calibration of other biological systems, particularly those related to self-regulation and resilience. Likewise, it will be useful to further examine the extent to which OXTR methylation is associated with enhanced modulation of response to stressors and better outcomes in the context of stress across adulthood, with potentially important implications for understanding the longer-term consequences of prevention for health, health behavior, and future relationship quality.