To investigate potential associations between rs7632287 and measures of marital quality other than the PBS and RQS scales, we used an item from a life event questionnaire based on the Social Readjustment Rating Scale (51) in the TOSS sample. This item asked whether the female subjects had experienced marital crisis or threat of divorce during the last year. We found that women carrying the A-allele more often answered affirmatively to this question than women not carrying this allele (Table 4a). Eleven percent of women carrying no copy of the A-allele reported marital crisis, whereas 16% of the women carrying this allele reported marital crisis, suggesting approximately a 50% increase in risk of marital crisis for carriers of the A-allele compared to noncarriers of this allele.
