In conclusion, with the advent of GWAS, exome and whole genome sequencing and a growing number of national genomics population studies and biobanks, there is now a huge volume of human genetic and functional data linked to disease traits. The challenge is integration and systematic analysis of this data to enable robust statistical associations and prioritisation of genes underlying disease causation. The Open Targets Genetics Portal addresses these challenges and provides the results in a unique open platform which can be queried programmatically or via an informative user interface. This enables users to address a wide range of research questions, and provides underlying evidence to aid drug discovery.
