women recruited from a variety of sources (e.g., bars, community centers, Alcoholics Anonymous meetings) had more lifetime antisocial personality disorder (ASPD) symptoms and scored higher on trait measures of antisocial disposition (e.g., MMPI-2 Psychopathic Deviance Scale) than did nonalcoholic controls, but did not differ from controls on 6 of 7 current ASPD symptoms, suggesting that antisocial behaviors were reduced and abstinence maintained despite an underlying antisocial disposition (25). Therefore, attempts to predict abstinent remission in a family member using lifetime AUD in another family member, a phenotype based in large part on externalizing behaviors which might not be observed in abstinent individuals, may not provide an optimal test of familial influences on remission, and may account for the null findings to date.
