and RNA expression levels8, measured using RNA-seq and gene expression microarrays (Fig. 2i). Our definition of 111 reference epigenomes is very similar to that used by the International Human Epigenome Consortium (IHEC), which required RNA-seq, WGBS, and H3K27ac that are only available in a subset of epigenomes here. Lastly, an additional 16 histone modification marks on average were profiled across 7 deeply-covered cell types (Fig. 2j).
