Chunk #35 — RESULTS — The unpaired presentation of stimuli lowers GluR1 immunoreactivity at axo-shaft asymmetric synapses

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Endogenous GluR1-containing AMPA receptors translocate to asymmetric synapses in the lateral amygdala during the early phase of fear memory formation: an electron microscopic immunocytochemical study.

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Taken together, these results show that fear conditioning increases both the levels of GluR1 immunoreactivity and the proportion of synapses immunoreactive for GluR1 subunits in the LA, but only when presented with the stimuli in a sequence that leads to the acquisition of predictive value for the CS and the conditioned response of freezing.