Chunk #21 — Online Methods — chromVAR algorithm — Variability

Source

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data.

Embedded

yes

Text

The variability of a TF motif across samples or cells was determined by computing the standard deviation of the z-scores across the cells or samples. The expected value of this metric is one if the motif peak sets are no more variable than the background peak sets for that motif.