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Chunk #11 — Current Work Attempting to Use iPS Cell Technology to Model AUDs

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Using human stem cells as a model system to understand the neural mechanisms of alcohol use disorders: Current status and outlook.
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accounts for ~ 40–60% of the risk to develop an AUD). However, the environment cannot be ignored which is illustrated by individuals adopted into an alcoholic household having the same risk of developing an AUD as those born to alcoholic parents. It would be naïve to think that it is either one or the other, but rather it is more likely that genetic and environmental factors together interact to dictate the occurrence and severity of alcohol dependence.