Chunk #21 — Discussion

Source

Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure.

Embedded

yes

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of nicotine leads to increased consumption to maintain circulating levels (55). However, evidence suggests that nicotine metabolism is inhibited in smokers compared with nonsmokers (56). We also did not adjust for other factors known to influence nicotine metabolism, such as sex and body mass index.