Jacobus et al. (2009). This study examined the status of WM integrity in youth with histories of AU and cannabis use. Youth (n = 42; ages 16–19) were grouped into one of the three categories: non-AU youth with very limited substance use history — “controls”, n = 14; AU youth who had had at least one binge drinking episode — “binge drinkers”, n = 14; and AU + MJ youth with one binge drinking episode and lifetime cannabis use — “binge drinkers + cannabis users”, n = 14. Here, we report results for only the AU versus non-AU youth comparisons. AU youth showed lower FA than non-AU youth across several WM regions, including superior corona radiata, inferior longitudinal fasciculus, inferior fronto-occipital fasciculus, superior longitudinal fasciculus. Measures of MD did not differ across groups.
