Coronary artery disease (coronary atherosclerosis) is a chronic degenerative condition in which lipid and fibrous matrix is deposited in the walls of the coronary arteries to form atheromatous plaques37. It may be clinically silent or present with angina pectoris or acute myocardial infarction. Pathogenesis is complex, with endothelial dysfunction, oxidative stress and inflammation contributing to development and instability of the atherosclerotic plaque37.
