Given the importance of peer influence for substance use, many preventive interventions are designed to assist adolescents’ abilities to make decisions that reduce exposure to and influence of substance-using peers. The data used here are drawn from the PROSPER project. Intervention communities delivered both family-focused and school-based interventions (Spoth et al., 2004). All intervention communities in PROSPER delivered the Strengthening Families Program: For Parents and Youth 10-14 (SFP 10-14) as their family-focused program. Approximately 17% of all eligible families across the PROSPER project’s two study cohorts participated in the SFP 10-14.