\usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\beta =Z/\sqrt{2{\rm{MAF}}\times (1-{\rm{MAF}})\times \left(N+{Z}^{2}\right)}$$\end{document}β=Z/2MAF×(1−MAF)×N+Z2 and SE = β/Z. Imputed GWAS summary statistics from these three studies are made publicly available on the GIANT consortium website (see ‘URLs’ section). We next performed a COJO analysis of all down-sampled GWAS using genotypes of 348,501 unrelated EUR participants in the UKB as a LD reference panel, as for our METAFE and EUR GWAS meta-analysis.
