a relatively rare and serious condition that can result in quadriplegia and curtailed longevity (Adams et al., 1959), is neuroradiologically defined on T2- weighted images as a hyperintense, triangular-shaped lesion in the middle of the pons (Kleinschmidt-DeMasters et al., 1997). Even in uncomplicated and asymptomatic alcoholics, prolonged T2 relaxation times indicative of excessive local interstitial fluid can be observed in the pons of older alcoholics, although more regularly in alcoholics with WKS (Sullivan and Pfefferbaum, 2001). Also consistent with the neuropathological literature is the MRI observation of white matter volume shrinkage in the cerebellum and pons of alcoholics (Sullivan et al., 1998; Sullivan, 2000; Sullivan and Pfefferbaum, 2001; Sullivan, 2003; Sullivan et al., 2003; Chanraud et al., 2007).
