The COGA, SAGE, and OZALC cohorts included a total of 8799 samples (6323 cases and 2476 controls; 50.6% were men and 49.4% were women). The AOU cohort had a total of 116 064 samples (5660 cases and 110 404 controls; 39.6% were men and 60.4% were women). The IB cohort had 6373 samples (936 cases and 5437 controls; 45.1% were men and 54.9% were women). A summary of the screening and testing datasets is presented in Table 1. The number of controls was much smaller than the number of cases in the screening datasets due to the definition of controls. The majority of AOU and IB samples were classified as controls.
