T25) was ~78% regardless of the FH. The impact of FH, however, was apparent among the high T1 drinking quantity group where the survival rate was lower for FHP (34%) compared to FHN (58%). Figure 4 illustrates the survival curves of AUD for the combinations of T1 drinking quantity and the age of drinking onset. Here, probands with high T1 drinking quantity, regardless of the age of drinking onset, had the lowest survival rates of being diagnosed with an AUD at ~47%. Those with an early onset and a low T1 drinking quantity had a survival rate of 71%, and the probands with neither risk factor (i.e. late onset and low T1 quantity) had the highest survival rate at 89%.
