dataset. QC included checking for sex inconsistencies and exclusions based on sample call rate <80%, SNP call rate <90% and exact Hardy-Weinberg Equilibrium (HWE) p<0.0001. In total, replication genotypes (in silico and de novo) of 76 prioritized SNPs and 27 AIMs were available from 2,677 AN cases and 8,629 controls of European ethnicity and 458 AN cases and 421 controls from Japan.