The findings of elevated odds of weekly CU and cannabis dependence among mixed-race individuals warrant research to monitor CU and CUD trends to inform intervention. The mixed-race population, especially children/adolescents, is the fastest growing population in the United States; and it is projected to increase from 8 million (2.5%) to 26 million (6.2% of the U.S. population) between 2014 and 2060, reflecting an increase of 228 % compared with an increase of 26% for the single-race population (Colby and Ortman, 2015). Although there is limited information about substance use disorders among mixed-race adults, an earlier study of youth 16–23 found that mixed-race youth had a particularly higher lifetime prevalence of illicit drug use than blacks and Hispanics (Wu et al., 2006). Recently, mixed-race adolescents were found to have a lower prevalence than whites of disapproving their peers’ CU as well as perceiving their parents’ and friends’ disapproval of adolescents’ own CU (Wu et al., 2015). In addition, disapproval of CU was associated with elevated odds of CU, and mixed-race adolescents had greater odds than white adolescents of using CU and