Chunk #20 — DISCUSSION

Source

Novel GABRG2 mutations cause familial febrile seizures.

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yes

Text

GABAA receptors mediate fast inhibitory synaptic transmission in the CNS. GABAA receptors are heteropentameric ligand-gated chloride channels combining 5 of 19 different subunits. The most common configuration in mammals requires 1 γ2 subunit in association with 2 α1-3 and 2 β2/3 subunits.21