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Chunk #0 — 1. INTRODUCTION

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The genetic relationship between cannabis and tobacco cigarette use in European- and African-American female twins and siblings.
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According to the most recent estimates from the National Survey of Drug Use and Health, 86.8% of lifetime cannabis users aged 12 and older reported a lifetime history of tobacco cigarette use while 61.7% of cigarette smokers also reported smoking cannabis during their lifetime (Substance Abuse and Mental Health Services Administration (SAMHSA), 2014). Adolescents reporting dual use are more likely to experience problems with both drugs, including rapid escalation to more involved stages of use and difficulty quitting (Agrawal et al., 2008; Peters et al., 2012; Timberlake et al., 2007).