precentral gyrus with age in response to negative vs. neutral words on an affective word task (Hardee et al., 2017). Adolescent females showed persistent activation in the amygdala and precentral gyrus with age in response to negative vs. neutral words (Hardee et al., 2017), a finding consistent with the notion that girls/women may be more reactive to negative emotional stimuli. Overall, SG-dependent alterations in frontal activation and limbic processing of negative stimuli may lead to differences in risk for AUD before adulthood (Hardee et al., 2017).
