inhibitor of nuclear factor kappa-B kinase subunit beta (IKKβ) as having a modulatory role in alcohol drinking. In a proof-of-concept study, Truitt and colleagues showed that pharmacological and genetic inhibition of IKKβ decreased voluntary ethanol consumption, providing initial support for IKKβ as a potential therapeutic target for alcohol abuse (Truitt et al., 2016), as well as functional evidence that gene network analysis is a viable approach to identify new treatments.
