Chunk #55 — Methods — In vivo point mutation assay
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As a positive control for the in vivo λ select-cII mutagenesis assay, mice were exposed to 150 mg kg−1 N-ethyl-N-nitrosourea (ENU, Sigma) in a single intraperitoneal injection on one occasion. Mice were allowed to recover and were euthanized 3 weeks later.