MOFAM is a longitudinal family study that included high-risk and low-risk subjects and was designed to investigate the impact of paternal alcoholism on offspring outcomes in an ethnically diverse sample of youth, with oversampling of AA families (55%) to increase the statistical power to detect differences in outcomes by race/ethnicity. As detailed elsewhere (Calvert et al., 2010), between 2003 and 2009, Missouri state birth records were used to identify families with at least one child aged 13, 15, 17 or 19 years (the same age range targeted in MOAFTS) and at least one full sibling aged 13 or older. Biological mothers completed brief telephone screening interviews to determine level of familial risk for alcoholism. Families in which the mother reported that the biological father had a history of excessive drinking were classified as “high risk.” All others were classified as “low risk.” An additional group of families was selected from men identified through driving records as having 2 or more drunk-driving convictions and classified as “very high risk.” Sample enrollment occurred over 6 years. A total of 731 females (of
