The MVP has been described in detail elsewhere (9). Briefly, it is an observational cohort study and mega-biobank supported by the VA. Data are collected from participants using questionnaires, the VA EHR, and a blood sample for genomic and other testing. We used AUDIT-C data collected from October 1, 2007 (when first available from EHR extracts) to May 1, 2017 and lifetime ICD diagnostic codes for AUD.