Participant characteristics, detailed procedures, recruitment details, and methods are described in detail elsewhere for both Study 1 (35, 36) and Study 2 (37, 38). We have reported previous analyses for some of these genes for both studies using point prevalence outcomes and continuous/prolonged abstinence, but heretofore we have not published results for time to first lapse in association with these variants (36). The following is a brief overview of both studies used in the current analyses.
