paperKB
coga / coga-kb
Help
Sign in

Chunk #31 — Conclusion

Source
Synthetic associations created by rare variants do not explain most GWAS results.
Embedded
yes

Text

the general conclusion that the likely causal gene is often located near the most strongly associated variant [6]. Genes identified through GWAS harbouring common variants are likely to be good targets for identification of rare variants and for sorting the wheat from the chaff in next generation sequencing studies. We expect that continued GWAS will make valuable contributions to our understanding of many complex traits and will, for some time, remain as one important tool in a growing set of technologies to probe the full spectrum of genetic variation efficiently.