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Chunk #22 — Results — Characteristics of type 2 diabetes cases

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Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study.
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Characteristics of ascertained and verified incident cases are shown in table 2; country specific information is provided in the online appendix (table ST3). Including the 2,577 of the 4,632 Danish cases with available blood samples that are not part of InterAct, the overall incidence in InterAct was 3.76 per 1000 person-years of follow-up, based on 14,980 verified diabetes cases occurring during 3,989,345 person-years. Crude incidences ranged from 1.4/ 1000 person-years in French women to 7.4/ 1000 (men 8.9, women 6.0) person-years in Denmark (online appendix; table ST3). For all analyses other than the calculation of crude and standardised incidence rates the 2,577 additional Danish cases are excluded, leading to a total of 12,403 InterAct cases (14,980-2,577=12,403). Of the 12,403 InterAct cases with an average follow-up of 6.9 years, 49.7% were men (n=6,165). Mean baseline age and age at diagnosis were 55.6 and 62.5 years, mean BMI and waist were 29.7 kg/m2 and 97.7 cm (29.4 kg/m2 and 102.7 cm in men, 30.1 kg/m2 and 92.8 cm in women), respectively (table 2). A total of 30.8% of all InterAct cases reported