Chunk #8 — Material and Methods — Genotyping, Imputation and Quality Control

Source

Genome-wide association analysis of opioid use disorder: A novel approach using clinical data.

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Post-imputation quality control was conducted to select high-quality SNPs and control for population stratification and family structure. The relatedness of the cohort was detected by pairwise IBD estimation, and 561 related patients were removed from the cohort.