we able to identify this replicated signal, highlighting the value of both a validation dataset and of joint analyses. Two additional datasets have found association of autism at 5p14.1. These include a cohort of 1,241 ASD cases and 6,491 control subjects and a cohort of 108 ASD cases and 540 controls. The combined p-values for SNPs in the 5p14.1 region in these datasets combined with ours, which includes over 10,000 subjects, range from 7.4×10-8 to 2.1×10-10. These results survive stringent Bonferroni correction. (Wang et al. 2008)