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Chunk #70 — DISCUSSION — Limitations

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Cross-frequency phase-amplitude coupling in repetitive movements in patients with Parkinson's disease.
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The resolution of PAC computation across the movement cycle is constrained by the minimum number of oscillatory cycles, which in turn, depends on the involved oscillation frequencies. Therefore, dynamic modulation of PAC cannot be resolved by the current analytic techniques during fast repetitive movements. In addition, separation of the movement cycles into discrete periods may not apply to everyday behavior, which in many instances is more appropriately conceived of as continuous action with no discrete transitions. It remains to be studied whether concepts derived from analyzing movement periods translate into the control of continuous movements.