We identified a highly significant excess of large, rare CNVs in children with ADHD compared with control participants, with the average number of CNVs per child with ADHD being 2·09 times higher than that in controls (p=8·9×10−5 table 1). 50 (14%) affected children were shown to carry a CNV larger than 500 kb, compared with 75 (7%) controls. In each of the ADHD and control samples, the rates of CNVs did not differ between male and female participants (data not shown; results available from NMW).
