et al., 2004; Kanayama et al., 2004), suggesting that users are less able to recruit the typical neural networks underlying complex cognitive functions and may require more neural resources to perform adequately. It is possible that diminutions in white matter caliber may be associated with this atypical processing tendency. Fiber pathways within and connecting superior medial and inferior frontal areas (Gruber and Yurgelun-Todd, 2005; Kanayama et al., 2004), temporal and parietal lobes (Grant et al., 2003), and the cerebellum including the tonsil (Chang et al., 2006) are implicated by structural and functional findings to show vulnerability to marijuana use.
