and targeting of H3K4me1 deposition around their binding sites. The observation that H3K4me1-marked regions in other tissues and cell types, including liver, erythrocytes, T cells and ES cells, also exhibit enrichment for limited sets of motifs for corresponding lineage determining factors (Figure S4C) suggests a general approach to the identification of such factors in distinct cell types, knowledge of which may facilitate cellular reprogramming efforts.
