paperKB
coga / coga-kb
Help
Sign in

Chunk #10 — IMPUTATION IN THE FUSION GENOMEWIDE ASSOCIATION STUDY

Source
MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes.
Embedded
yes

Text

the fine-mapping panel, 96.24% in the candidate gene panel, and 98.73% in the low MAF SNP panel. Furthermore, the average r2 between imputed genotypes and actual genotypes was 90.4, 79.1, and 74.0% in the three SNP panels, respectively. This represents an improvement of 14–39% compared to the best available single marker tags, which provided an average r2 of 76.5, 52.8, and 35.5% in the three SNP panels, respectively.