Participant characteristics according to smoking status are presented in Table 1. At baseline, prevalence of current smokers was 32% for NHS, 12.8% for NHS II, and 10.3% for HPFS. Compared to never smokers, current smokers were more likely to consume more alcohol and caffeine, reported a higher prevalence of regular use of antidepressants and minor tranquilizers, and a lower prevalence of married/partnership status.