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Chunk #76 — Discussion

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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010.
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water connections over improved water sources. Similarly, we did not find a significantly improved effect of water quality interventions, consistent with the findings reported by Cairncross and colleagues,128 which showed that masked point-of-use water quality interventions did not have a significant effect on self-reported diarrhoea. As a result of this reassessment, we restricted our analysis to improved water and improved sanitation compared with unimproved sources following the MDG definitions. However, the interventions used in previous studies might not have achieved their full efficacy because of the quality of implementation. The real burden from water and sanitation could therefore be underestimated if well-implemented household connect ions and water quality interventions have a larger effect than improved water sources alone, and if the combination of poor water and sanitation has a larger effect than a sample interaction of individual effects. More definitive epidemiological evidence is needed to assess the effects of low quality versus high quality water, household connections versus improved water sources, and exposure based on travel time to water source.175 Also, we could not include an assessment of personal hygiene because of the paucity of national exposure data.