In 2009, Paul Thompson initiated the ENIGMA (Enhancing Neuroimaging and Genetics through Meta‐analysis) consortium. ENIGMA has now grown to a collaboration of more than 1,400 scientists from 43 countries studying the human brain, both in health and disease (Thompson et al., 2019). The initial aim was to perform large‐scale neuroimaging genetics analyses, by pooling worldwide data, resources and expertise, to answer clinical and fundamental questions related to psychiatric and neurological disorders. The consortium currently has 30 working groups on specific psychiatric and neurological disorders, a few on trans‐diagnostic constructs (e.g., irritability, suicidality, and lifespan), and 12 that develop and disseminate analysis pipelines, to facilitate harmonization across working groups.
