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Chunk #29 — Glossary

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Polygenic risk scores in psychiatry: Will they be useful for clinicians?
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yes

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Oligogenic: Oligogenic inheritance represents an intermediary between monogenic inheritance (in which a trait is determined by a single causative gene) and polygenic inheritance (in which a trait is influenced by many genes and often environmental factors as well). It describes a condition where a small number of genes determine the trait, linkage is not detected using Mendelian models, and phenotype–genotype correlation can be improved by inclusion of genotypes from another locus (or loci).