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Chunk #49 — Long-range connectivity — Misconnectivity

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Psychosis related to neurological conditions: pro and cons of the dis- / mis-connectivity models of schizophrenia.
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However the amount of psychosis in misconncction diseases is mild. It could also not be the causal factor, as most of these disorders are accompanied by epilepsy. But from an other perspective, the psychosis of epilepsy has not been found to be related to dysplasia.108 Another confounding factor could be the presence of WM lesions in most misconnection diseases. As an example, both tuberous sclerosis and neurofibromatosis also come with WM abnormalities that could account for the expression of psychosis.109-110