These probands were originally recruited as 18–25 year old (mean age ~20) Caucasian drinking but not alcohol dependence men through questionnaires mailed to random students and nonacademic staff at the University of California, San Diego between 1978 and 1988 (Schuckit & Gold, 1988; Schuckit & Smith, 2000). Potential participants were subsequently evaluated in person with a semi-structured interview based on the Renard Diagnostic Interview and the Structured Clinical Diagnostic Interview (SCID) of the Diagnostic and Statistical Manual of Mental Disorders (DSM; American Psychiatric Association, 1987). All probands participated in an alcohol challenge with 0.75ml/kg (0.61gm/kg) of ethanol, consumed over 8–10 minutes, to evaluate their LR over three hours through self reports of subjective feelings of intoxication, alterations in body sway/standing steadiness, and alcohol-related changes in cortisol (Schuckit & Gold, 1988; Schuckit & Smith, 2000).
