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Chunk #40 — Discussion

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Ancestry informative marker sets for determining continental origin and admixture proportions in common populations in America.
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assignment. For larger studies (sample sizes of several thousand) the precision of individual assignments will be less consequential than for smaller studies in which the investigation will be more dependent on the accurate assessment of ancestry of each individual. Thus choice of the number of SNP AIMs depends on the populations being studied as well as practical aspects of genotyping. However, as shown in our study, the 96 In4 SNP AIMs perform well for each of the potential applications with only a very modest reduction of potential information compared with the 128 In4 set. Even smaller numbers perform adequately in particular situations but may require additional confidence in the prior information i.e. confidence in self identification of population membership.