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Chunk #12 — Materials and methods — Gene-set enrichment analysis

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Multi-omics signatures of alcohol use disorder in the dorsal and ventral striatum.
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Gene-set enrichment analysis was performed using the R package fgsea (v.1.12.0) [30], for which DE genes were ranked according to p-value. Enrichment analysis was performed for Gene-Ontology (GO) terms [31] and Hallmark gene sets [32] and the results were adjusted using FDR correction.