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Chunk #29 — Results — Source Localization

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Resting-state EEG source localization and functional connectivity in schizophrenia-like psychosis of epilepsy.
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Fig. 1 shows the averaged eLORETA solutions. Electric neuronal activity was higher in patients with SLPE compared to nonpsychotic patients for the slower frequency bands. Higher current density maxima were found particularly in delta (SLPE: 1.59±1.04, nPE: 1.35±0.98), theta (SLPE: 0.97±0.88, nPE: 0.50±0.24) as well as in the lower alpha band (SLPE: 0.76±1.13, nPE: 0.66±1.07). There was a similar cortical distribution of maximal activity across groups; delta and theta bands had maximum values in the prefrontal cortex, whereas alpha1 activity was maximal in occipital regions. Theta oscillations were also observed over the parietal cortex in patients with SLPE. Pronounced slow oscillatory activity was not seen in temporal sites. The nonpsychotic group exhibited slightly higher source current density maxima for the rest of the frequency bands, with alpha2 (SLPE: 0.20±0.14, nPE: 0.25±0.10) maxima in the occipital cortex, and beta1 (SLPE: 0.41±0.25, nPE: 0.48±0.29) and beta2 (SLPE: 0.34±0.16, nPE: 0.46±0.37) maxima observed over the lateral prefrontal cortex. The statistical analysis revealed significant differences between groups exclusively in the theta band, patients with SLPE exhibiting significantly increased current density in the theta frequency