and behavioral problems were also documented. We identified 575 cases with cardiovascular defects, 1,776 cases with epilepsy/seizure disorder, 1,379 cases with autism spectrum disorder, 3,898 cases with craniofacial defects, and 8,772 cases with general neurological defects; many individuals had multiple subclassifications (Supplementary Table 2). Self-reported ethnicity was available for 144 individuals, with 75% (95% CI 67.3–81.4%, 108/144) reporting Caucasian (primarily European descent), 6.9% (95% CI 3.8–12.3% 10/144) African American, and 18.1% (95% CI 12.6–25.1% 26/144) as other. These samples were analyzed across nine custom array-CGH platforms, with most tested on an Agilent array with ~97,000 probes (Supplementary Figure 13).
