GWAS has had many successes. Many common polymorphisms have now been found that increase genetic risk for AD (Harold et al. 2009; Lambert et al. 2009; Naj et al. 2011), age-related cognitive decline (Davies et al. 2012), schizophrenia (Almasy et al. 2008; Stefansson et al. 2009; Ripke et al. 2011; Rietschel et al. 2012), bipolar disorder (Sklar et al. 2011; Cichon et al. 2011) as well as obesity (Yang et al. 2012), alcohol drinking (Schumann et al. 2011), tobacco smoking (Thorgeirsson et al. 2008), cardiovascular disease (CARDIoGRAMplusC4D Consortium et al. 2013), osteoporosis (Estrada et al. 2012), prevalent psychiatric disorders (Cross-Disorder Group of the Psychiatric Genomics Consortium et al. 2013) and for many other traits and diseases.
