Genetic epidemiology reveals that genes account for more than 80% of the population variance in risk (1,2) of schizophrenia (SCZD[MIM 181500]). Numerous genetic associations to schizophrenia have been reported, but it remains widely disputed which of these, if any, are true associations (3). The advent of genome-wide association study (GWAS) technology has recently proven to be successful in allowing the identification of strongly supported genetic associations for many other common phenotypes, and this is now true for schizophrenia(4,5,6,7)
